Semaglutide and Digestive Health: What You Need to Know About Constipation
4/5/2026
Semaglutide is effective for weight loss — but like any medication, it can come with side effects.
Constipation is one of the more common GI side effects of semaglutide. Here are proven strategies to manage it.
Increase fiber gradually
Aim for 25-35g of fiber per day from fruits, vegetables, and whole grains.
Stay well hydrated
Target at least 64 oz of water daily.
Move your body
Light daily activity keeps digestion moving.
When to contact your doctor
If constipation lasts more than a week or is painful, message your Willow physician.